Inspired by the American psychological drama film directed by Darren Aronofsky and starring Jarred Leto. It is based on the 1978 novel of the same name by Hubert Selby Jr., with whom Aronofsky wrote the screenplay. The film depicts four characters affected by drug addiction and how it alters their physical and emotional states. Their addictions cause them to become imprisoned in a world of delusion and desperation. As the film progresses, each character deteriorates, and their delusions are shattered by the harsh reality of their situations, resulting in Catastrophe.